Publications
10. Shipp LE, Hill RZ, Hamdoun A. A teaching laboratory on the activation of xenobiotic transporters at fertilization of sea urchins. Methods in Cell Biology - Echinoderms Part A. 2019; 150: 429-447. Link to Article. PDF
9. Gökırmak T, Campanale JP, Reitzel AM, Shipp LE, Moy GW, Hamdoun A. Functional diversification of sea urchin ABCC1 (MRP1) by alternative splicing. American Journal of Physiology – Cell Physiology. 2016 Jun; 310 (11): C911-920. Link to Article. PDF
8. *°Shipp LE, Hill RZ, Moy GW, Gökırmak T, Hamdoun A. ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos. Development. 2015 Oct; 142 (20): 3537-3548. Link to Article. PDF
°Featured as Editors’ Choice in Science Signaling. 2015 Oct 27; 8 (400) ec310.
7. *Gökırmak T, Shipp LE, Campanale JP, Nicklisch SC, Hamdoun A. Transport in technicolor: Mapping ATP-binding cassette transporters in sea urchin embryos. Molecular Reproduction and Development. 2014 Sep; 81 (9): 778-793. Link to Article. PDF
6. Gökırmak T, Campanale JP, Shipp LE, Moy GW, Tao H, Hamdoun A. Localization and substrate selectivity of sea urchin multidrug (MDR) efflux transporters. Journal of Biological Chemistry. 2012 Dec; 287 (52): 43876-83. Link to Article. PDF
5. Shipp LE, Hamdoun A. ATP-binding cassette (ABC) transporter expression and localization in sea urchin development. Developmental Dynamics. 2012 Jun; 241 (6); 1111-1124. Link to Article. PDF
4. Shipp LE, Lee JV, Yu CY, Pufall M, Zhang P, Scott DK, Wang JC. Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS One. 2010 Oct 29; 5 (10): e13754. Link to Article. PDF
3. Roohk DJ, Varady KA, Turner SM, Emson CL, Gelling RW, Shankaran M, Lindwall G, Shipp LE, Scanlan TS, Wang JC, Hellerstein MK. Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone. Journal of Pharmacology and Experimental Therapeutics. 2010 Apr; 333 (1): 281-289. Link to Article. PDF
2. Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV Jr, Wang JC. Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. Journal of Biological Chemistry. 2009 Sep 18; 284 (38): 25593-601. Link to Article. PDF
1. Patek SN, Shipp LE, Staaterman E. The acoustics and acoustic behavior of the California spiny lobster (Panulirus interruptus). Journal of the Acoustical Society of America. 2009 May; 125 (5): 3434-43. Link to Article. PDF
Confocal micrograph of a pluteus-stage sea urchin embryo. The hindgut is in the centre. Shown are plasma membranes (yellow), a fluorescent dye (blue) used to track ATP-binding cassette (ABC) transporter activity, and pigment cells (red) that express the transporter ABCC5a, which is required for hindgut invagination.
Shipp LE, Hill RZ, Moy GW, Gökırmak T, Hamdoun A. ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos. Development. 2015 Oct; 142 (20): 3537-3548.